Ensuring the testosterone dose is not too high will reduce the side effects further.ĥ. Minoxidil may help to prevent hair loss and grow back some lost hair. Finasteride can be used in men to prevent DHT conversion in the scalp – this can cause side effects of its own in men and should be used with caution and consideration.ģ. Smaller, more frequent doses may lead to less spikes in testosterone and therefore DHT which means less of these side effects.Ģ. Over time these follicles will stop producing hair.ġ. DHT affects the hairs primarily at the top and front of the scalp near the temples. The DHT in the scalp shrinks the hair follicle and may cause it to stop growing hair over time. Androgenic alopecia/male pattern baldness – TRT can accelerate certain types of baldness that occur in men. This change in the prostate is caused by DHT, which is metabolized by the type II 5-alpha-reductase enzyme.Ĥ. Prostate growth – It is well known that men who start TRT may get a small amount of prostate growth and a rise in PSA, this usually reduces after the first few months of treatment. This is most common when levels of testosterone and oestrogen are spiking.ģ. Increased spots or acne – TRT can increase sebum production which leads to more spots and acne in some men. Other men will want this effect to an extent.Ģ. Excess body hair growth – also known as hirsutism, this can be an undesirable side effect of TRT. If too high it can cause unwanted side effects.ġ. The more body fat you have, the more conversion of testosterone into oestrogen will occur.ĭHT is a metabolite of testosterone – its volume increases with higher testosterone levels. Lose body fat – body fat contains high levels of aromatase. Tamoxifen may be used in some cases to block the oestrogen receptors in the breast tissue and prevent issues with gynaecomastia and nipple irritation.ħ. Aromatase inhibitors act on the aromatase enzyme to prevent the conversion of testosterone into oestrogen.Ħ. Using compounds such as Cypionate and Enanthate with less fast-acting esters which increase oestrogen spikes.ĥ. Smaller doses rather than large ones reduce that amount of oestrogen converted from testosterone.Ĥ. Higher frequency of injections with a lower dose reduces spikes in oestrogen levels.ģ. Prevention is better than a cure – the best way to stop oestrogen related side effects is to use a protocol that prevents oestrogen build-up.Ģ. ![]() There are a few ways to treat this issue, some require medications whereas others use changes to the way testosterone is administered.ġ. Most side effects from TRT are easily treated, and raised oestrogen is no exception. How to deal with common side effects of oestrogen from TRT Low mood – as with anxiety, high oestrogen levels can make men feel down. Anxiety – in some men, raised oestrogen can cause anxiety.Ħ. High oestrogen makes men more emotional – crying at things they wouldn’t usually find very emotional is a common complaint.ĥ. Increased emotional lability – this means being more emotional than usual. ![]() This can be a serious side effect if left untreated in men with heart conditions.Ĥ. It is often seen by men on TRT as an increase in weight or swollen ankles. ![]() This is a common side effect of TRT and a good indicator that oestrogen levels are raised. Water retention – high oestrogen levels can cause water retention. This process usually starts with sensitive of itchy nipples.ģ. Nipple itchiness or gynaecomastia – raised oestrogen can also cause the irritation, and later growth, of breast tissue. If oestrogen is raised then men often experience fatigue.Ģ. This is usually when the dose is too high or someone converts a lot of testosterone into oestrogen. Fatigue – counterintuitively, TRT can cause fatigue. The most common side effects of TRT are usually related to increased levels of oestrogen, DHT and testosterone.
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